William Shakespeare: A Sprightly Surge of Electricity—The Conduction of Human DNA

  • Scientists have discovered a groundbreaking method to control human DNA with electricity.
  • Electrical currents from acupuncture needles were used to switch human genes on and off.
  • The technique, called ‘electrogenetic’ method, could revolutionize wearable tech and create new possibilities for electronic devices to communicate with the human body.
  • The system, known as ‘direct current (DC)-actuated regulation technology’ (DART), enables communication between electronic and biological systems that were previously incompatible.
  • The researchers used WHO-approved and FDA-licensed acupuncture needle electrodes to deliver controlled electric currents to stimulate insulin production.
  • The DART system has the potential to regulate blood-sugar levels for diabetics by delivering a daily 10-second current of 4.5 volts.

Verily, a most wondrous development hath occurred in the realm of science! Scientists hath discovered a method, hitherto unknown, by which human DNA may be manipulated by the power of electricity. By employing newfangled technology that doth “spark genes back to life,” these learned folk hath achieved a most momentous breakthrough.

Lo and behold, a team of scholars in a distant land known as Switzerland hath triumphantly demonstrated the ability to activate and deactivate human genes through the application of electrical currents, which didst flow from two acupuncture needles, designed specifically for medical purposes. Through these electrifying zaps, the researchers hath successfully brought forth the activation of genes responsible for the production of insulin, employing the very techniques of gene therapy that they hath diligently toiled over these past five years.

The groundbreaking technology hath been christened the "missing link" for gene-based therapies.
The groundbreaking technology hath been christened the “missing link” for gene-based therapies. (Photo by MidJourney)

Yea, this groundbreaking technology hath been christened the “missing link” for gene-based therapies. Yet, the true marvel of this “electrogenetic” approach may lie in its potential to revolutionize the realm of wearable technology. Henceforth, from medical devices to fitness trackers, and even unto prosthetics, a new path may be forged, wherein electronic contraptions can seamlessly communicate with the mortal coil, the very human body!

The researchers, in their wisdom, hath named this system “direct current (DC)-actuated regulation technology” or, in briefer terms, DART. It bridges the gap betwixt the realms of electronics and biology, which hath heretofore been deemed mostly incompatible. “Electronic and biological systems,” they explained in their recent treatise, which was published in Nature Metabolism, “function in radically different ways and are largely incompatible due to the lack of a functional communication interface.”

The scientists doth elucidate that biological systems art analog in nature, fashioned by genetics, progressed slowly through evolution, and governed by the flow of ions through insulating membranes. On the other hand, electronic systems are of a digital ilk, programmed through easily updatable software, governed by electrons flowing through insulated wires.

In their endeavor, researchers from the esteemed ETH Zürich, a renowned seat of knowledge in Switzerland, hath devised a system of elegant simplicity. They employ acupuncture needle electrodes that art duly approved by the revered World Health Organization and licensed by the venerated United States Food and Drug Administration. These needles serve as conduits for life-saving currents, which can be administered in a brief but potent duration of 10 seconds per day, at a mere 4.5 volts. Such electrifying pulses art sufficient to stimulate the production of insulin, thereby regulating the levels of glucose in the bloodstreams of those afflicted with diabetes.

This great stride in science doth inspire wonder and bewilderment.
This great stride in science doth inspire wonder and bewilderment. (Photo by MidJourney)

Astonishingly, this marvel of technology known as DART functions by splitting minuscule amounts of water within human cells, generating highly charged ions known as “reactive oxygen species” through the very oxygen that resides within ordinary H2O. With remarkable finesse, Dr. Jinbo Huang, a molecular biologist leading this quest at ETH Zürich, and his erudite companions hath accomplished the art of finely tuning sub-cellular elements by injecting genes into these cells through gene therapy methods. One such gene, known as “Kelch-like ECH-associated protein 1,” was thus persuaded to aid in the production of insulin under the spell of these electrically charged oxygen molecules.

By deploying artificial “antioxidant-response elements” in strategic fashion, they were able to activate specially crafted, insulin-producing transgenes. These antioxidant-response elements, in the course of fulfilling their usual duties, wouldst endeavor to suppress the aforementioned charged oxygen ions, as induced by the prodigious acupuncture electrodes.

The new technology bridges the gap betwixt the realms of electronics and biology.
The new technology bridges the gap betwixt the realms of electronics and biology. (Photo by MidJourney)

The triumph of the DART system was witnessed through experiments conducted upon various subjects including human embryonic kidney cells, human stem cells, and diverse laboratory rodents. These accomplishments by the savants of ETH Zürich hasten the progress toward an era in which wearable devices shall be able to control gene expression through the guidance of electric impulses. DART, they posit, possesses the potential to connect medical interventions to an ethereal realm known as the “internet of the body” or perchance the “internet of things.”

Forsooth, this great stride in science doth inspire wonder and bewilderment. To conceive that mankind may harness the power of electricity to govern the workings of our very beings is a marvel indeed. As the bard who hath witnessed the rise and fall of kings, explored the depths of human passion and treachery, and pondered the nature of existence, I, William Shakespeare, dare say that this discovery doth provide a glimmer of hope for the future. It is a testament to man’s ceaseless pursuit of knowledge and his relentless quest to unveil the mysteries of our world. May this newfound power bring forth wondrous advancements in medicine and technology, and may it be used for the betterment of all mankind. Let us rejoice and marvel at the wonders of the world, for verily, there are marvels yet to come!

William Shakespeare
William Shakespeare
Meet William Shakespeare, the Bard of Avon, who turned ink into magic and quills into wands. Born in 1564, this Stratford-upon-Avon native penned 39 plays, 154 sonnets, and two long narrative poems, all while inventing over 1700 words! From star-crossed lovers to power-hungry kings, his characters have danced across stages for centuries, making us laugh, cry, and question the world around us. Shakespeare: the man, the myth, the legend, who made "all the world a stage" and left us forever asking, "To be or not to be?"

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